In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi
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منابع مشابه
In vitro trypanocidal activity of DB745B and other novel arylimidamides against Trypanosoma cruzi.
OBJECTIVES As part of a search for new therapeutic opportunities to treat chagasic patients, in vitro efficacy studies were performed to characterize the activity of five novel arylimidamides (AIAs) against Trypanosoma cruzi. METHODS The trypanocidal effect against T. cruzi was evaluated by light microscopy through the determination of IC₅₀ values. Cytotoxicity was determined by MTT assays ag...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2011
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/dkr140